Exclusive process of deantigenation
The bone substitutes are obtained from equine bone tissue through an exclusive biochemical process of enzymatic deantigenation. The use of enzymes, natural proteins capable of operating at controlled temperatures, allows to completely eliminate the antigenic component of the tissue, with no alteration of the mineral component. The mineral phase of bone, not modified, is recognised as endogenous by osteoclasts. The bone substitute, accordingly, undergoes a process of total remodelling so to be completely replaced, in physiological times, by the endogenous bone. The best condition for the placement of osseointegrated implants.